Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL27636636 | 0.98 | CYP1A2 (0.57) | CYP1A2CYP2C19CYP2D6CYP2C9TDP1 | |
| SCHEMBL47 | 0.95 | CYP1A2 (0.59) | CYP1A2CYP2C19CYP2D6CYP2C9TDP1 | |
| SCHEMBL30365968 | 0.95 | CYP1A2 (0.59) | CYP1A2CYP2C19CYP2D6CYP2C9TDP1 | |
| Phosphine SCHEMBL28240107 | 0.93 | CYP1A2 (0.57) | CYP1A2CYP2C19CYP2D6CYP2C9TDP1 | |
| SCHEMBL29140496 | 0.93 | CYP1A2 (0.57) | CYP1A2CYP2C19CYP2D6CYP2C9TDP1 | |
| Hydrogen Sulfide SCHEMBL28763519 | 0.93 | CYP1A2 (0.57) | CYP1A2CYP2C19CYP2D6CYP2C9TDP1 | |
| Naphthalene SCHEMBL28758695 | 0.93 | CYP1A2 (0.57) | CYP1A2CYP2C19CYP2D6CYP2C9TDP1 | |
| SCHEMBL27347238 | 0.93 | CYP1A2 (0.57) | CYP1A2CYP2C19CYP2D6CYP2C9TDP1 | |
| Water SCHEMBL8463988 | 0.93 | CYP1A2 (0.57) | CYP1A2CYP2C19CYP2D6CYP2C9TDP1 | |
| SCHEMBL28214959 | 0.93 | CYP1A2 (0.57) | CYP1A2CYP2C19CYP2D6CYP2C9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1716095-B | Radiation sensitive resin composition, cured resin and liquid crystal display device | SUMITOMO CHEMICAL CO | 2011-05-18 | — | — | CN | disclosed |
| CN-1716095-A | Radiation sensitive resin composition, cured resin and liquid crystal display device | SUMITOMO CHEM ENG (JP) | 2006-01-04 | — | — | CN | disclosed |
| CN-1715303-A | Copolymer and its preparing method | SUMITOMO CHEMICAL CO (JP) | 2006-01-04 | — | — | CN | disclosed |