Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944832 | 0.82 | HTT (0.48) | BRD4IDO1FGFR1FGFR2ABL1 | |
| SCHEMBL10397598 | 0.68 | IDO1 (0.66) | IDO1 | |
| SCHEMBL30581184 | 0.68 | IDO1 (0.66) | IDO1 | |
| SCHEMBL3945684 | 0.68 | HTT (0.41) | BRD4IDO1ABL1RAD52RIN1 | |
| SCHEMBL15845607 | 0.67 | IP6K1 (0.55) | BRD4IDO1 | |
| SCHEMBL3234194 | 0.66 | PARP1 (0.63) | FGFR1ABL1RAD52RIN1 | |
| SCHEMBL13946131 | 0.66 | HTT (0.58) | IDO1HTT | |
| SCHEMBL29554478 | 0.66 | HTT (0.58) | IDO1HTT | |
| SCHEMBL31721711 | 0.64 | IP6K1 (0.55) | BRD4IDO1 | |
| SCHEMBL10355357 | 0.64 | IDO1 (0.58) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1633436-A | Pyrrolopyrimidine derivatives | TEIJIN LTD (JP) | 2005-06-29 | — | — | CN | disclosed |