SCHEMBL27617873

SCHEMBL27617873

CC(C)C(C(N)=O)S(=O)(=O)O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.31
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL424702 0.77 TDP1 (0.35) SLC7A5
SCHEMBL4829066 0.72
SCHEMBL27608536 0.72
Isobutyramide SCHEMBL29045865 0.71 BLM (0.42) SLC7A5CA14
Isobutyramide SCHEMBL6490900 0.69 CA14 (0.39) CA14
Sulfuric Acid SCHEMBL11225308 0.69 TP53 (0.42) CA14
Sulfuric Acid SCHEMBL8412324 0.69 TP53 (0.41) SLC7A5CA14
Sulfuric Acid SCHEMBL8412325 0.69 TP53 (0.41) SLC7A5CA14
SCHEMBL6856744 0.69 TSHR (0.33)
SCHEMBL27886721 0.69 CA14 (0.33) CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102083839-A Compound (I) ASTRAZENECA AB 2011-06-01 CN disclosed
CN-100384824-C Acetyl 2-hydroxy-1, 3-diaminoalkanes PHARMACIA & UPJOHN CO LLC (US) 2008-04-30 CN disclosed
CN-1694870-A Acetyl 2-hydroxy-1, 3-diaminoalkanes PHARMACIA & UPJOHN CO LLC (US) 2005-11-09 CN disclosed