Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486704 | 0.82 | KDM4E (0.42) | HSD17B10HPGDMAPTKDM4ETDP1 | |
| SCHEMBL10884650 | 0.79 | HSD17B10 (0.53) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL3686834 | 0.73 | HPGD (0.50) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL5132602 | 0.73 | ELANE (0.52) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL30631651 | 0.72 | MAPT (0.59) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL10778989 | 0.72 | MAPT (0.59) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL28363001 | 0.71 | ELANE (0.50) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL4363059 | 0.70 | HPGD (0.58) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL1254116 | 0.70 | KMT2A (0.64) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL4527922 | 0.69 | MAPT (0.54) | HSD17B10HPGDALOX15MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100529842-C | Highly safe silicone-containing material for ocular lens and process for producing the same | MENICON CO LTD (JP) | 2009-08-19 | — | — | CN | disclosed |
| CN-1723411-A | High-safety ophthalmic lens material containing silicone and method for producing same | MENICON CO LTD (JP) | 2006-01-18 | — | — | CN | disclosed |