Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14188294 | 0.83 | MAPKAPK2 (0.62) | MAPKAPK2HDAC1FYNALDH1A1 | |
| SCHEMBL14188328 | 0.82 | MAPKAPK2 (0.62) | MAPKAPK2HDAC1KDM1AKDM4CHDAC6 | |
| Trifluoroacetic Acid SCHEMBL4714055 | 0.78 | MAPKAPK2 (0.57) | MAPKAPK2HDAC1ALDH1A1 | |
| SCHEMBL27639060 | 0.78 | MAPKAPK2 (0.67) | MAPKAPK2HDAC1KDM1AKDM4CHDAC6 | |
| Trifluoroacetic Acid SCHEMBL4791161 | 0.78 | MAPKAPK2 (0.56) | MAPKAPK2HDAC1KDM1AKDM4CHDAC6 | |
| SCHEMBL4712817 | 0.77 | MAPKAPK2 (0.55) | MAPKAPK2HDAC1KDM1AKDM4CHDAC6 | |
| SCHEMBL27620303 | 0.77 | MAPKAPK2 (0.62) | MAPKAPK2ALDH1A1 | |
| SCHEMBL14188284 | 0.76 | MAPKAPK2 (0.64) | MAPKAPK2HDAC1KDM4CHDAC6FYN | |
| Hydrochloric Acid SCHEMBL4715203 | 0.76 | MAPKAPK2 (0.54) | MAPKAPK2HDAC1KDM1AKDM4CHDAC6 | |
| SCHEMBL14188371 | 0.76 | MAPKAPK2 (1.00) | MAPKAPK2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1747949-A | Acyclic pyrazole compounds | PHARMACIA CORP (US) | 2006-03-15 | — | — | CN | disclosed |