Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Triethyl Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triethyl Phosphate SCHEMBL38651170 | 1.00 | TSHR (0.72) | TSHRTP53TDP1PPARDCYP3A4 | |
| Triethyl Phosphate SCHEMBL10358522 | 0.92 | TSHR (0.77) | TSHRTP53TDP1PPARDCYP3A4 | |
| Triethyl Phosphate SCHEMBL27815382 | 0.86 | TSHR (0.68) | TSHRTP53TDP1PPARDCYP3A4 | |
| Triethyl Phosphate SCHEMBL23045857 | 0.85 | TSHR (0.59) | TSHRTP53TDP1PPARDCYP3A4 | |
| Triethyl Phosphate SCHEMBL1332591 | 0.85 | TSHR (1.00) | TSHRTP53TDP1PPARDCYP3A4 | |
| Triethyl Phosphate SCHEMBL21887 | 0.85 | TSHR (1.00) | TSHRTP53TDP1PPARDCYP3A4 | |
| Triethyl Phosphate SCHEMBL27822049 | 0.85 | TSHR (1.00) | TSHRTP53TDP1PPARDCYP3A4 | |
| Triethyl Phosphate SCHEMBL28023664 | 0.85 | TSHR (1.00) | TSHRTP53TDP1PPARDCYP3A4 | |
| Triethyl Phosphate SCHEMBL28949387 | 0.84 | TSHR (0.56) | TSHRTP53TDP1PPARDCYP3A4 | |
| Triethyl Phosphate SCHEMBL28464376 | 0.82 | TSHR (0.81) | TSHRTP53TDP1PPARDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117757046-A | Disperse dye easy-to-dye functional polyester and preparation method thereof | 徐州斯尔克纤维科技股份有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-122059824-A | Synthesis method of ilalastyl chiral intermediate | 上海格苓凯生物科技有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-119744352-A | Intracellular ligation of photocatalysts for photoresponsive, probe-mediated protein labeling | 美国锡德治疗有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-115872923-B | Compound and preparation method thereof | 成都泰和伟业生物科技有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-115872923-A | Compound and preparation method thereof | 成都泰和伟业生物科技有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-113956449-B | Multifunctional graphene polyester and preparation method thereof | 徐州斯尔克纤维科技股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-108242559-B | Electrolyte solution, electrochemical device, lithium ion secondary battery, and assembly | 大金工业株式会社 | 2022-06-07 | — | — | CN | disclosed |
| CN-113956449-A | Multifunctional graphene polyester and preparation method thereof | 徐州斯尔克纤维科技股份有限公司 | 2022-01-21 | — | — | CN | disclosed |
| CN-101268079-B | Pyridazinone derivatives for the treatment of pain | ASTELLAS PHARMA INC | 2011-09-14 | — | — | CN | disclosed |
| CN-101121779-B | Polymerization catalyst for polyester, process for producing the catalyst, and process for producing polyester using the catalyst | MITSUBISHI CHEM CORP | 2010-07-28 | — | — | CN | disclosed |
| CN-101268079-A | Pyridazinone derivatives for the treatment of pain | ASTELLAS PHARMA INC (JP) | 2008-09-17 | — | — | CN | disclosed |
| CN-101121779-A | Polymerization catalyst for polyester, process for producing the catalyst, and process for producing polyester using the catalyst | MITSUBISHI CHEM CORP (JP) | 2008-02-13 | — | — | CN | disclosed |
| CN-100341918-C | Polymerization catalyst for polyester, process for producing the catalyst, and process for producing polyester using the catalyst | MITSUBISHI CHEM CORP (JP) | 2007-10-10 | — | — | CN | disclosed |
| CN-1756788-A | Polymerization catalyst for polyester, process for producing the catalyst, and process for producing polyester using the catalyst | MITSUBISHI CHEM CORP (JP) | 2006-04-05 | — | — | CN | disclosed |