SCHEMBL27620166

SCHEMBL27620166

Cc1c[c]c2cc3ccc(C)cc3cc2c1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 6/20 0.52
CYP1A2 P05177 6/20 0.52
TDP1 Q9NUW8 1/20 0.45
ALDH1A1 P00352 2/20 0.33
NCK1 P16333 1/20 0.33
BACE1 P56817 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CA12 O43570 3/20 0.32
CA9 Q16790 3/20 0.32
NQO2 P16083 1/20 0.32
MAPT P10636 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27639240 1.00 CYP2A6 (0.52) CYP2A6CYP1A2TDP1ALDH1A1NCK1
SCHEMBL2698723 0.86 CYP2A6 (0.46) CYP2A6CYP1A2TDP1ALDH1A1HPGD
SCHEMBL667864 0.85 CYP1A2 (0.52) CYP2A6CYP1A2TDP1ALDH1A1NCK1
SCHEMBL666751 0.83 CYP2A6 (0.48) CYP2A6CYP1A2TDP1ALDH1A1NCK1
SCHEMBL31612403 0.78 CYP1A2 (0.87) CYP2A6CYP1A2TDP1ALDH1A1NCK1
SCHEMBL6888140 0.78 CYP1A2 (0.87) CYP2A6CYP1A2TDP1ALDH1A1NCK1
SCHEMBL2490023 0.78 CYP1A2 (0.87) CYP2A6CYP1A2TDP1ALDH1A1NCK1
SCHEMBL6056946 0.78 CYP1A2 (0.87) CYP2A6CYP1A2TDP1ALDH1A1NCK1
SCHEMBL4368477 0.78 CYP1A2 (0.87) CYP2A6CYP1A2TDP1ALDH1A1NCK1
SCHEMBL29837229 0.78 CYP1A2 (0.87) CYP2A6CYP1A2TDP1ALDH1A1NCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100478364-C Ethylene polymer and molded article obtained therefrom MITSUI CHEMICALS INC (JP) 2009-04-15 CN disclosed
CN-1732189-A Ethylene polymer and molded article obtained therefrom MITSUI CHEMICALS INC (JP) 2006-02-08 CN disclosed