Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13640491 | 0.91 | MME (0.41) | GABRR1CYP1A2MMEFFAR3FOLH1 | |
| SCHEMBL3463057 | 0.80 | EPHX1 (0.43) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL7107840 | 0.76 | OR51E2 (0.40) | FFAR3TP53 | |
| SCHEMBL28777371 | 0.74 | GRM1 (0.47) | CYP1A2 | |
| SCHEMBL22363343 | 0.74 | GRM1 (0.47) | CYP1A2 | |
| Hydrochloric Acid SCHEMBL22636220 | 0.73 | GRM1 (0.46) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL22636222 | 0.73 | GRM1 (0.46) | ALDH1A1 | |
| SCHEMBL15307474 | 0.71 | GABRR1 (0.39) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL13798393 | 0.71 | GABRR1 (0.39) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL13185383 | 0.71 | FFAR3 (0.58) | FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100462351-C | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2009-02-18 | — | — | CN | disclosed |
| CN-1817854-A | Amino acids with affinity for the alpha-2-delta protein | WARNER LAMBERT CO (US) | 2006-08-16 | — | — | CN | disclosed |
| CN-1653036-A | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2005-08-10 | — | — | CN | disclosed |