Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.56 |
| ▸ | CA2 | P00918 | 11/20 | 0.56 |
| ▸ | CA9 | Q16790 | 8/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL219170 | 0.97 | — | — | |
| SCHEMBL2791299 | 0.90 | CA1 (0.60) | CA1CA2CA9CA12CA7 | |
| SCHEMBL10478711 | 0.88 | CA1 (0.61) | CA1CA2CA9CA12CA7 | |
| SCHEMBL29137295 | 0.88 | CA1 (0.61) | CA1CA2CA9CA12CA7 | |
| SCHEMBL8411185 | 0.88 | CA1 (0.61) | CA1CA2CA9CA12CA7 | |
| SCHEMBL11510742 | 0.88 | CA1 (0.61) | CA1CA2CA9CA12CA7 | |
| SCHEMBL5265837 | 0.88 | CA1 (0.61) | CA1CA2CA9CA12CA7 | |
| SCHEMBL3270913 | 0.81 | — | — | |
| Fluoride SCHEMBL28098238 | 0.77 | TSHR (0.70) | CA1CA2CA9CA12CA7 | |
| SCHEMBL19733 | 0.76 | CA1 (0.64) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104144922-B | 2H-indazoles as EP 2 receptor antagonists | 拜耳知识产权有限责任公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-102712552-B | Method for production of F-18 labeled glutamic acid derivatives | Bayer Pharma AG | 2015-07-22 | — | — | CN | disclosed |
| CN-104144922-A | As EP2Novel 2H-indazoles as receptor antagonists | BAYER IP GMBH | 2014-11-12 | — | — | CN | disclosed |
| CN-102105444-B | Process for producing perfluoroalkyl sulfinate | CENTRAL GLASS CO LTD | 2013-08-07 | — | — | CN | disclosed |
| CN-102712575-A | Homoglutamic acid derivatives | BAYER SCHERING PHARMA AG | 2012-10-03 | — | — | CN | disclosed |
| CN-102712552-A | Method for production of F-18 labeled glutamic acid derivatives | BAYER SCHERING PHARMA AG | 2012-10-03 | — | — | CN | disclosed |
| CN-102239130-A | Radioisotope-labeled lysine and ornithine derivatives, their use and preparation method | BAYER SCHERING PHARMA AG | 2011-11-09 | — | — | CN | disclosed |
| CN-102105444-A | Process for producing perfluoroalkyl sulfinate | CENTRAL GLASS CO LTD | 2011-06-22 | — | — | CN | disclosed |
| CN-101092401-A | Stereoselective alkylation of chiral 2-methyl-4-protected piperazines | SCHERING CORP (US) | 2007-12-26 | — | — | CN | disclosed |
| CN-100343240-C | Stereoselective alkylation of chiral 2-methyl-4-protected piperazines | SCHERING CORP (US) | 2007-10-17 | — | — | CN | disclosed |
| CN-1642930-A | Stereoselective alkylation of chiral 2-methyl-4-protected piperazines | SCHERING CORP (US) | 2005-07-20 | — | — | CN | disclosed |