Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620790 | 0.96 | C5AR1 (0.59) | C5AR1SMN1; SMN2LMNAL3MBTL1PPARG | |
| SCHEMBL649243 | 0.95 | C5AR1 (0.60) | C5AR1SMN1; SMN2LMNAL3MBTL1PPARG | |
| SCHEMBL648344 | 0.94 | C5AR1 (0.63) | C5AR1SMN1; SMN2LMNAL3MBTL1PPARG | |
| SCHEMBL651150 | 0.93 | C5AR1 (0.61) | C5AR1SMN1; SMN2LMNAL3MBTL1PPARG | |
| SCHEMBL647696 | 0.93 | C5AR1 (0.57) | C5AR1SMN1; SMN2LMNAL3MBTL1PPARG | |
| SCHEMBL649697 | 0.92 | C5AR1 (0.57) | C5AR1SMN1; SMN2LMNAL3MBTL1HTR2A | |
| SCHEMBL649030 | 0.92 | C5AR1 (0.60) | C5AR1SMN1; SMN2LMNAL3MBTL1PPARG | |
| SCHEMBL652971 | 0.91 | C5AR1 (0.56) | C5AR1SMN1; SMN2LMNAL3MBTL1PPARG | |
| SCHEMBL650856 | 0.91 | C5AR1 (0.56) | C5AR1SMN1; SMN2LMNAL3MBTL1PPARG | |
| SCHEMBL649488 | 0.91 | C5AR1 (0.56) | C5AR1SMN1; SMN2LMNAL3MBTL1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1646497-A | Novel arylimidazoles and related compounds as modulators of the C5a receptor | NEUROGEN CORP (US) | 2005-07-27 | — | — | CN | claimed |