Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DTYMK | P23919 | 1/20 | 0.42 |
| ▸ | DNA2 | P51530 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2213952 | 0.82 | TSHR (0.62) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL21802325 | 0.80 | TSHR (0.58) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1533771 | 0.77 | TSHR (0.44) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16049739 | 0.76 | TDP1 (0.41) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28423348 | 0.76 | TSHR (0.58) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11569981 | 0.76 | PDE7A (0.46) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11920168 | 0.76 | TSHR (0.53) | TSHRMAPTALDH1A1GAATDP1 | |
| SCHEMBL9657224 | 0.75 | TSHR (0.53) | TSHRMAPTALDH1A1MEN1KMT2A | |
| Thiocyanic Acid SCHEMBL27796510 | 0.74 | TSHR (0.56) | TSHRMAPTALDH1A1MEN1KMT2A | |
| Acetonitrile SCHEMBL28323453 | 0.74 | TSHR (0.60) | TSHRMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8592216-B2 | Labeling peptides with tertiary amines and other basic functional groups for improved mass spectrometric analysis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-11-26 | — | — | US | claimed |
| US-20100330680-A1 | LABELING PEPTIDES WITH TERTIARY AMINES AND OTHER BASIC FUNCTIONAL GROUPS FOR IMPROVED MASS SPECTROMETRIC ANALYSIS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-12-30 | — | — | US | claimed |
| US-9770500-B2 | S-nitrosylation of glucosylating toxins and uses therefor | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-09-26 | — | — | US | disclosed |
| US-8592216-B2 | Labeling peptides with tertiary amines and other basic functional groups for improved mass spectrometric analysis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-11-26 | — | — | US | disclosed |
| US-20130005690-A1 | S-NITROSYLATION OF GLUCOSYLATING TOXINS AND USES THEREFOR | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-01-03 | — | — | US | disclosed |
| WO-2012166991-A1 | S-NITROSYLATION OF GLUCOSYLATING TOXINS AND USES THEREFOR | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEEM (US) | 2012-12-06 | — | — | WO | disclosed |
| US-20100330680-A1 | LABELING PEPTIDES WITH TERTIARY AMINES AND OTHER BASIC FUNCTIONAL GROUPS FOR IMPROVED MASS SPECTROMETRIC ANALYSIS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-12-30 | — | — | US | disclosed |
| WO-1991019804-A1 | SYSTEM FOR EXPRESSING A POLYPEPTIDE SEQUENCE AND EXPOSING IT ON THE SURFACE OF A HOST CELL | INSTITUT PASTEUR (FR) | 1991-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100330680-A1 | LABELING PEPTIDES WITH TERTIARY AMINES AND OTHER BASIC FUNCTIONAL GROUPS FOR IMPROVED MASS SPECTROMETRIC ANALYSIS | PTMS, VIP, NGLY1 | TSHR 284/4885MAPT 2568/4885ALDH1A1 3718/4885 |
| US-20130005690-A1 | S-NITROSYLATION OF GLUCOSYLATING TOXINS AND USES THEREFOR | ENGASE, UGCG, NOX1 | TSHR 2128/4885MAPT 4567/4885ALDH1A1 1868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.