Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 20/20 | 0.98 |
| ▸ | PIK3CD | O00329 | 19/20 | 0.98 |
| ▸ | PIK3CB | P42338 | 15/20 | 0.98 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2762514 | 0.99 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL2780819 | 0.93 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL2781914 | 0.92 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL2781870 | 0.92 | PIK3CG (0.84) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL2781519 | 0.92 | PIK3CG (0.86) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL2780678 | 0.89 | PIK3CG (0.81) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL2780438 | 0.89 | PIK3CG (0.83) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL3346291 | 0.88 | PIK3CG (0.80) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL2783009 | 0.88 | PIK3CG (0.84) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL2782486 | 0.87 | PIK3CG (0.78) | PIK3CGPIK3CDPIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010092015-A1 | UREA TRIAZOLOLO [1, 5-A] PYRIDINE DERIVATIVES AS PI3K INHIBITORS | CELLZOME LIMITED (GB) | 2010-08-19 | — | — | WO | claimed |
| WO-2010092015-A1 | UREA TRIAZOLOLO [1, 5-A] PYRIDINE DERIVATIVES AS PI3K INHIBITORS | CELLZOME LIMITED (GB) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010092015-A1 | UREA TRIAZOLOLO [1, 5-A] PYRIDINE DERIVATIVES AS PI3K INHIBITORS | CELLZOME LIMITED (GB) | 2010-08-19 | — | — | WO | disclosed |