Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 20/20 | 0.72 |
| ▸ | CNR2 | P34972 | 15/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27623926 | 0.89 | CNR1 (0.70) | CNR1CNR2KCNH2 | |
| SCHEMBL5234811 | 0.86 | CNR1 (0.84) | CNR1CNR2KCNH2 | |
| SCHEMBL5236621 | 0.84 | CNR1 (0.80) | CNR1CNR2KCNH2 | |
| SCHEMBL15200900 | 0.84 | CNR1 (1.00) | CNR1CNR2KCNH2 | |
| SCHEMBL15201068 | 0.84 | CNR1 (0.89) | CNR1CNR2 | |
| SCHEMBL15200793 | 0.84 | CNR1 (1.00) | CNR1CNR2KCNH2 | |
| SCHEMBL15200826 | 0.83 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL5237529 | 0.83 | CNR1 (0.77) | CNR1CNR2KCNH2 | |
| SCHEMBL15200804 | 0.83 | CNR1 (1.00) | CNR1CNR2KCNH2 | |
| SCHEMBL21847870 | 0.82 | CNR1 (0.72) | CNR1CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100439369-C | Purine compounds and their use as cannabinoid receptor ligands | PFIZER (US) | 2008-12-03 | — | — | CN | claimed |
| CN-1784243-A | A pharmaceutical composition for the prevention and treatment of nicotine addiction in a mammal | PFIZER PROD INC (US) | 2006-06-07 | — | — | CN | claimed |
| CN-1708499-A | Purine compounds and their use as cannabinoid receptor ligands | PFIZER (US) | 2005-12-14 | — | — | CN | claimed |
| CN-100478343-C | Purine compound and use as cannabinoid receptor ligands | PFIZER (US) | 2009-04-15 | — | — | CN | disclosed |
| CN-100439369-C | Purine compounds and their use as cannabinoid receptor ligands | PFIZER (US) | 2008-12-03 | — | — | CN | disclosed |
| CN-1955182-A | Purine compound and use as cannabinoid receptor ligands | PFIZER (US) | 2007-05-02 | — | — | CN | disclosed |
| CN-1955181-A | Purine compound and use as cannabinoid receptor ligands | PFIZER (US) | 2007-05-02 | — | — | CN | disclosed |
| CN-1784243-A | A pharmaceutical composition for the prevention and treatment of nicotine addiction in a mammal | PFIZER PROD INC (US) | 2006-06-07 | — | — | CN | disclosed |
| CN-1708499-A | Purine compounds and their use as cannabinoid receptor ligands | PFIZER (US) | 2005-12-14 | — | — | CN | disclosed |