Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.73 |
| ▸ | AKR1B1 | P15121 | 8/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3009395 | 0.91 | PTGDR2 (0.76) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1406036 | 0.86 | PTGDR2 (0.79) | PTGDR2AKR1B1CYP2C9SLC6A4 | |
| SCHEMBL28755766 | 0.86 | PTGDR2 (0.69) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1406169 | 0.84 | PTGDR2 (0.76) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1406026 | 0.84 | PTGDR2 (1.00) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1406010 | 0.83 | PTGDR2 (0.73) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL5361236 | 0.82 | PTGDR2 (0.82) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1406116 | 0.77 | PTGDR2 (0.79) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1405915 | 0.77 | PTGDR2 (0.65) | PTGDR2AKR1B1CYP2C9SLC6A4 | |
| SCHEMBL1406070 | 0.77 | PTGDR2 (0.74) | PTGDR2AKR1B1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100404505-C | Novel substituted indoles | ASTRAZENECA AB (SE) | 2008-07-23 | — | — | CN | claimed |
| CN-1671659-A | Novel substituted indoles | ASTRAZENECA AB (SE) | 2005-09-21 | — | — | CN | claimed |
| CN-100404505-C | Novel substituted indoles | ASTRAZENECA AB (SE) | 2008-07-23 | — | — | CN | disclosed |
| CN-1671659-A | Novel substituted indoles | ASTRAZENECA AB (SE) | 2005-09-21 | — | — | CN | disclosed |