Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196858 | 0.89 | MAPT (0.61) | MAPTKDM4ETDP1CYP3A4MAPK1 | |
| SCHEMBL8026821 | 0.85 | GSK3B (0.48) | MAPTCYP3A4MAPK1SMN1; SMN2MEN1 | |
| SCHEMBL3918774 | 0.82 | MAPT (0.52) | MAPTKDM4ETDP1CYP3A4MAPK1 | |
| SCHEMBL8026820 | 0.81 | KMT2A (0.45) | MAPTKDM4ETDP1CYP3A4MAPK1 | |
| SCHEMBL29557420 | 0.81 | AKR1B1 (0.61) | MAPTKDM4ETDP1SMN1; SMN2HPGD | |
| SCHEMBL197933 | 0.81 | AKR1B1 (0.61) | MAPTKDM4ETDP1SMN1; SMN2HPGD | |
| Bicarbonate SCHEMBL31055577 | 0.80 | KDM4E (0.53) | MAPTKDM4ETDP1CYP3A4MAPK1 | |
| Bicarbonate SCHEMBL27658688 | 0.80 | KDM4E (0.53) | MAPTKDM4ETDP1CYP3A4MAPK1 | |
| Bicarbonate SCHEMBL27658689 | 0.80 | KDM4E (0.53) | MAPTKDM4ETDP1CYP3A4MAPK1 | |
| SCHEMBL593745 | 0.80 | MAPT (0.50) | MAPTKDM4ETDP1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100410234-C | Catalyst for asymmetric synthesis using chiral Bronsted acid and asymmetric synthesis method using the same | TOAGOSEI CO LTD (JP) | 2008-08-13 | — | — | CN | disclosed |
| CN-1780810-A | Asymmetric-synthesis catalyst based on chiral broensted acid and method of asymmetric synthesis with the catalyst | TOAGOSEI CO LTD (JP) | 2006-05-31 | — | — | CN | disclosed |