SCHEMBL276272

SCHEMBL276272

Oc1ncsn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1997544 0.57
Potassium SCHEMBL30168527 0.56
SCHEMBL2638687 0.50
SCHEMBL28508440 0.48
Hydrochloric Acid SCHEMBL1026361 0.48
SCHEMBL5007434 0.47
SCHEMBL4584646 0.45
SCHEMBL13523738 0.44
SCHEMBL24459 0.44
Hydrochloric Acid SCHEMBL546609 0.42

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5843997-A Excitatory amino acid receptor antagonists ELI LILLY AND COMPANY (US) 1998-12-01 US claimed
WO-1997023471-A1 5-DIFLUOROMETHOXY-3-ARYL-1,2,4-THIADIAZOL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS NEMATICIDE AGENTS BASF AKTIENGESELLSCHAFT (DE) 1997-07-03 WO claimed
US-5576323-A CENTRAL NERVOUS SYSTEM DISORDERS ELI LILLY AND COMPANY (US) 1996-11-19 US claimed
EP-0658539-A1 Excitatory amino acid receptor antagonists ELI LILLY AND COMPANY (US) 1995-06-21 EP claimed
EP-4168002-A1 METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS Revolution Medicines, Inc. (US) 2023-04-26 EP disclosed
US-20210284627-A1 INDOLE COMPOUNDS AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2021-09-16 US disclosed
EP-3766877-A1 INDOLE COMPOUND AND PHARMACEUTICAL USE THEREOF Japan Tobacco Inc. (JP) 2021-01-20 EP disclosed
US-20200255408-A1 INDOLE COMPOUNDS AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2020-08-13 US disclosed
US-20180362506-A1 INDOLE COMPOUNDS AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2018-12-20 US disclosed
US-20170267662-A1 INDOLE COMPOUNDS AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2017-09-21 US disclosed
EP-2759533-B1 CONDENSED HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2017-08-02 EP disclosed
EP-2499691-B1 METHOD FOR MECHANICALLY STABILIZING NITROGEN-CONTAINING POLYMERS SAMSUNG ELECTRONICS CO LTD (KR) 2017-07-12 EP disclosed
US-20050159438-A1 Spirocyclic heterocyclic derivatives and methods of their use ADOLOR CORPORATION 2005-07-21 US disclosed
WO-2005033073-A2 SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE ADOLOR CORPORATION (US) 2005-04-14 WO disclosed
US-5843997-A Excitatory amino acid receptor antagonists ELI LILLY AND COMPANY (US) 1998-12-01 US disclosed
WO-1997023471-A1 5-DIFLUOROMETHOXY-3-ARYL-1,2,4-THIADIAZOL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS NEMATICIDE AGENTS BASF AKTIENGESELLSCHAFT (DE) 1997-07-03 WO disclosed
US-5576323-A CENTRAL NERVOUS SYSTEM DISORDERS ELI LILLY AND COMPANY (US) 1996-11-19 US disclosed
EP-0658539-A1 Excitatory amino acid receptor antagonists ELI LILLY AND COMPANY (US) 1995-06-21 EP disclosed
US-5210204-A Hypotensive agents and cardiovascular disorders WARNER-LAMBERT COMPANY (US) 1993-05-11 US disclosed
US-3943144-A INSECTICIDE, MITICIDE CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed