Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28758636 | 0.85 | PPARG (0.52) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL14281016 | 0.80 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL27627365 | 0.79 | POLB (0.48) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL8620864 | 0.79 | MAPT (0.44) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL27627290 | 0.79 | PPARG (0.63) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL27627289 | 0.78 | POLB (0.52) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL27627283 | 0.77 | MAPT (0.49) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL27627287 | 0.77 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL27647652 | 0.76 | MAPT (0.44) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL3279523 | 0.75 | MAPT (0.39) | NPC1RAB9ASMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1761787-A | Oxidation system comprising macrocyclic metal complexes, method for the production and use thereof | LANXESS B V (NL) | 2006-04-19 | — | — | CN | disclosed |