Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 13/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652461 | 0.82 | GCK (0.72) | GCKPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2652460 | 0.82 | GCK (0.72) | GCKPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2666084 | 0.82 | GCK (0.66) | GCKPTPN1DUSP3PTPN11PTPN22 | |
| SCHEMBL2649861 | 0.81 | GCK (0.70) | GCKPTPN1DUSP3PTPN11PTPN22 | |
| SCHEMBL2649863 | 0.81 | GCK (0.70) | GCKPTPN1DUSP3PTPN11PTPN22 | |
| SCHEMBL3389108 | 0.80 | GCK (0.76) | GCKPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2666082 | 0.80 | GCK (0.76) | GCKPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2651710 | 0.79 | GCK (0.71) | GCKAKR1C3POLBNPC1RAB9A | |
| SCHEMBL2651705 | 0.79 | GCK (0.71) | GCKAKR1C3POLBNPC1RAB9A | |
| SCHEMBL2650624 | 0.79 | GCK (1.00) | GCKPOLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1809561-A | Phenylacetamides and their use as glucokinase modulators | PROSIDION LTD (GB) | 2006-07-26 | — | — | CN | claimed |