Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279710 | 0.89 | CYP2C19 (0.41) | CYP2C19HIF1AMAPTHDAC3HDAC4 | |
| SCHEMBL3281050 | 0.88 | CYP2C19 (0.41) | CYP2C19HIF1AMAPTHDAC3HDAC4 | |
| SCHEMBL3278666 | 0.87 | CYP2C19 (0.51) | CYP2C19HIF1AMAPTHDAC3HDAC4 | |
| SCHEMBL3279812 | 0.87 | CYP2C19 (0.42) | CYP2C19HIF1AMAPTHDAC3HDAC4 | |
| SCHEMBL3286984 | 0.86 | CYP2C19 (0.41) | CYP2C19HIF1AMAPTHDAC3HDAC4 | |
| SCHEMBL3280257 | 0.86 | CYP2C19 (0.53) | CYP2C19HIF1AMAPTHDAC3HDAC4 | |
| SCHEMBL3278389 | 0.86 | CYP2C19 (0.43) | CYP2C19HIF1AMAPTHDAC3HDAC4 | |
| SCHEMBL5162333 | 0.86 | CYP2C19 (0.47) | CYP2C19HIF1AMAPTHDAC3HDAC4 | |
| SCHEMBL3333881 | 0.85 | CYP2C19 (0.42) | CYP2C19HIF1AMAPTHDAC3HDAC4 | |
| SCHEMBL3279773 | 0.84 | CYP2C19 (0.55) | CYP2C19HIF1AMAPTHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678297-A | Method of treating osteoarthritis | WARNER LAMBERT CO (US) | 2005-10-05 | — | — | CN | disclosed |