Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12288900 | 0.82 | PTGER3 (0.47) | PTGER4PTGER3PTGER2 | |
| SCHEMBL2241761 | 0.82 | PTGER3 (0.47) | PTGER4PTGER3PTGER2 | |
| SCHEMBL13204793 | 0.81 | PTGER4 (0.43) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5814319 | 0.80 | PTGER3 (0.53) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6683022 | 0.80 | PTGER3 (0.53) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5902707 | 0.78 | PTGER4 (0.40) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5902794 | 0.78 | PTGER4 (0.39) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5072194 | 0.73 | PTGER2 (0.39) | PTGER4PTGER3PTGER2 | |
| SCHEMBL11711444 | 0.73 | PTGER2 (0.41) | PTGER4PTGER3PTGER2 | |
| SCHEMBL7886844 | 0.73 | PTGER2 (0.41) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1764659-A | Prostaglandin analogs as EP4 receptor antagonists | MERCK FROSST CANADA LTD (CA) | 2006-04-26 | — | — | CN | claimed |
| CN-1764659-A | Prostaglandin analogs as EP4 receptor antagonists | MERCK FROSST CANADA LTD (CA) | 2006-04-26 | — | — | CN | disclosed |