Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 7/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4852853 | 0.83 | PPARD (0.53) | PPARDPPARGPPARA | |
| SCHEMBL27650476 | 0.80 | PPARD (0.54) | PPARDKDM4EMEN1HSP90AA1MAPT | |
| SCHEMBL27630406 | 0.76 | PPARD (0.47) | PPARDKDM4EMEN1HSP90AA1MAPT | |
| SCHEMBL3372091 | 0.74 | PPARD (0.47) | PPARDKIF11KDM4EMEN1HSP90AA1 | |
| SCHEMBL3065978 | 0.72 | CYP11B1 (0.47) | KDM4EMEN1MAPTKMT2ANPC1 | |
| SCHEMBL5691394 | 0.72 | PPARD (0.46) | PPARDKIF11KDM4EMEN1HSP90AA1 | |
| SCHEMBL3370403 | 0.71 | PPARD (0.45) | PPARDKIF11KDM4EMEN1HSP90AA1 | |
| SCHEMBL15109598 | 0.71 | PPARD (0.45) | PPARDKIF11NPC1ALDH1A1GAA | |
| SCHEMBL2096650 | 0.71 | PPARD (0.47) | PPARDKIF11KDM4EMEN1HSP90AA1 | |
| SCHEMBL5692060 | 0.69 | PPARD (0.43) | PPARDKIF11KDM4EMEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1809541-A | Aniline derivatives | HOFFMANN LA ROCHE (CH) | 2006-07-26 | — | — | CN | claimed |
| CN-1809541-A | Aniline derivatives | HOFFMANN LA ROCHE (CH) | 2006-07-26 | — | — | CN | disclosed |