SCHEMBL2763071

SCHEMBL2763071

CC12CC3(C)CC(c4ccc(C56CC7(C)CC(C)(C5)CC(c5ccc(C#Cc8ccccc8)c(C#Cc8ccccc8)c5)(C7)C6)cc4)(C1)CC(c1ccc(C#Cc4ccccc4)c(C#Cc4ccccc4)c1)(C2)C3

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GRM5 P41594 6/20 0.31
PTPN1 P18031 1/20 0.30
PTPN11 Q06124 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2763187 0.94 KCNH2 (0.34) APPKDM4EMEN1NPC1ALDH1A1
SCHEMBL2763104 0.92 APP (0.32) APPKDM4EMEN1NPC1ALDH1A1
SCHEMBL2763025 0.87 APP (0.33) APPKDM4EMEN1NPC1ALDH1A1
SCHEMBL2763858 0.84 APP (0.38) APPNPC1CYP3A4MAPTGRM5
SCHEMBL2846334 0.82 RARB (0.36) APPKDM4EMEN1NPC1ALDH1A1
SCHEMBL2763049 0.82 KCNH2 (0.33) APPKDM4EMEN1NPC1ALDH1A1
SCHEMBL4065062 0.79 APP (0.39) APPMAPTGRM5
SCHEMBL2762805 0.79 GRIN2D (0.47) MEN1ALDH1A1KMT2A
SCHEMBL2764292 0.78 KCNH2 (0.37) APPKDM4EMEN1NPC1ALDH1A1
SCHEMBL2763805 0.78 RARB (0.35) APPCYP3A4GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530596-B2 Polymer for forming insulating film, composition for forming insulating film, insulating film, and electronic device having same SUMITOMO BAKELITE CO., LTD. (JP) 2013-09-10 US disclosed
US-20100130672-A1 POLYMER FOR FORMING INSULATING FILM, COMPOSITION FOR FORMING INSULATING FILM, INSULATING FILM, AND ELECTRONIC DEVICE HAVING SAME SUMITOMO BAKELITE CO., LTD. (JP) 2010-05-27 US disclosed
EP-2177545-A1 POLYMER FOR FORMING INSULATING FILM, COMPOSITION FOR FORMING INSULATING FILM, INSULATING FILM, AND ELECTRONIC DEVICE HAVING INSULATING FILM Sumitomo Bakelite Company Limited (JP) 2010-04-21 EP disclosed