⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27842331 | 1.00 | — | — | |
| SCHEMBL3630003 | 0.81 | — | — | |
| SCHEMBL6953341 | 0.81 | — | — | |
| SCHEMBL27880625 | 0.78 | — | — | |
| SCHEMBL11772717 | 0.74 | — | — | |
| SCHEMBL27763848 | 0.74 | — | — | |
| SCHEMBL27857211 | 0.74 | — | — | |
| SCHEMBL4075706 | 0.73 | — | — | |
| SCHEMBL13708229 | 0.72 | — | — | |
| SCHEMBL709728 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1809557-A | Compound | ASTRAZENECA AB (SE) | 2006-07-26 | — | — | CN | claimed |
| CN-1809557-B | Compound | ASTRAZENECA AB | 2012-07-04 | — | — | CN | disclosed |
| CN-1950351-B | 3- or 4-monosubstituted phenol and thiophenol derivatives useful as h3 ligands | WARNER LAMBERT CO | 2012-01-18 | — | — | CN | disclosed |
| CN-100491372-C | Substituted quinazoline derivatives as inhibitors of aurora kinase | ASTRAZENECA AB (SE) | 2009-05-27 | — | — | CN | disclosed |
| CN-1898234-A | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases | INCYTE CORP (US) | 2007-01-17 | — | — | CN | disclosed |
| CN-1835945-A | Chinazoline derivatives as aurora kinase inhibitors | ASTRAZENECA AB (SE) | 2006-09-20 | — | — | CN | disclosed |
| CN-1809557-A | Compound | ASTRAZENECA AB (SE) | 2006-07-26 | — | — | CN | disclosed |