Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 17/20 | 0.68 |
| ▸ | EGFR | P00533 | 2/20 | 0.65 |
| ▸ | BTK | Q06187 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL656865 | 0.89 | SYK (0.68) | SYKEGFRBTK | |
| SCHEMBL31294168 | 0.85 | SYK (0.79) | SYKEGFR | |
| SCHEMBL656467 | 0.85 | SYK (0.79) | SYKEGFR | |
| SCHEMBL656182 | 0.85 | SYK (0.74) | SYKEGFR | |
| SCHEMBL656609 | 0.84 | SYK (0.70) | SYKEGFR | |
| SCHEMBL655465 | 0.83 | SYK (0.73) | SYKEGFR | |
| SCHEMBL656636 | 0.83 | SYK (0.68) | SYKEGFRBTK | |
| SCHEMBL655437 | 0.82 | SYK (0.76) | SYKEGFRBTK | |
| SCHEMBL656301 | 0.81 | SYK (0.69) | SYKEGFRBTK | |
| SCHEMBL654741 | 0.81 | SYK (0.75) | SYKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678321-A | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | CN | disclosed |