Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 3/20 | 0.41 |
| ▸ | CCND1 | P24385 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29453277 | 0.91 | TSHR (0.69) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| SCHEMBL931955 | 0.91 | TSHR (0.69) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| SCHEMBL6628956 | 0.89 | TSHR (0.67) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| Hydrochloric Acid SCHEMBL20610213 | 0.89 | TSHR (0.67) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| Bromide SCHEMBL19150274 | 0.89 | TSHR (0.67) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| Iodide SCHEMBL30801070 | 0.89 | TSHR (0.67) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| Methane SCHEMBL1173679 | 0.89 | TSHR (0.67) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| Oxalic Acid SCHEMBL9806412 | 0.87 | TSHR (0.65) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| Cyanide SCHEMBL22418732 | 0.85 | TSHR (0.62) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| SCHEMBL27631979 | 0.84 | NOTUM (0.61) | TSHRRAB9AL3MBTL1NOTUMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678306-A | -3 (sulfonamidoethyl) -indole derivaties for use as glucocorticoid mimetics in the treatment of inflammatory, allergic and proliferative diseases | BOEHRINGER INGELHEIM PHARMA (US) | 2005-10-05 | — | — | CN | disclosed |