Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.64 |
| ▸ | TNF | P01375 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443518 | 1.00 | HPRT1 (0.64) | HPRT1TNFALDH1A1HSD17B10TDP1 | |
| SCHEMBL27620091 | 0.98 | HPRT1 (0.67) | HPRT1TNFALDH1A1HSD17B10TDP1 | |
| SCHEMBL13505946 | 0.96 | HPRT1 (0.58) | HPRT1TNFALDH1A1HSD17B10TDP1 | |
| SCHEMBL2835699 | 0.93 | HPRT1 (0.67) | HPRT1TNFALDH1A1HSD17B10TDP1 | |
| SCHEMBL2592231 | 0.91 | HPRT1 (0.58) | HPRT1TNFALDH1A1HSD17B10TDP1 | |
| SCHEMBL2589946 | 0.91 | HPRT1 (0.58) | HPRT1TNFALDH1A1HSD17B10TDP1 | |
| SCHEMBL28589121 | 0.91 | HPRT1 (0.58) | HPRT1TNFALDH1A1HSD17B10TDP1 | |
| SCHEMBL30332725 | 0.91 | HPRT1 (0.58) | HPRT1TNFALDH1A1HSD17B10TDP1 | |
| SCHEMBL30332938 | 0.91 | HPRT1 (0.64) | HPRT1TNFALDH1A1HSD17B10TDP1 | |
| SCHEMBL27937443 | 0.91 | TNF (0.59) | HPRT1TNFALDH1A1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104876902-B | 7-cyclohexylmethyl-5- (2' -amino) phenyl chrysin and preparation method and application thereof | 大连理工大学 | 2017-06-27 | — | — | CN | claimed |
| CN-104876902-A | 7-cyclohexane methyl-5- (2' -amino) phenyl chrysin and preparation method and application thereof | UNIV DALIAN TECH | 2015-09-02 | — | — | CN | claimed |
| CN-104876902-B | 7-cyclohexylmethyl-5- (2' -amino) phenyl chrysin and preparation method and application thereof | 大连理工大学 | 2017-06-27 | — | — | CN | disclosed |
| CN-104876902-B | 7-cyclohexylmethyl-5- (2' -amino) phenyl chrysin and preparation method and application thereof | 大连理工大学 | 2017-06-27 | — | — | CN | disclosed |
| CN-104876902-A | 7-cyclohexane methyl-5- (2' -amino) phenyl chrysin and preparation method and application thereof | UNIV DALIAN TECH | 2015-09-02 | — | — | CN | disclosed |
| CN-1678321-A | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | CN | disclosed |