Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741253 | 0.86 | MEN1 (0.50) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL5741250 | 0.86 | MEN1 (0.50) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5744501 | 0.85 | MEN1 (0.49) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5744492 | 0.85 | MEN1 (0.49) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL5992968 | 0.83 | MEN1 (0.52) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL5992976 | 0.83 | MEN1 (0.52) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL22516782 | 0.83 | MEN1 (0.49) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL5991491 | 0.82 | HDAC1 (0.60) | MEN1KMT2A | |
| SCHEMBL30985375 | 0.82 | HDAC1 (0.60) | MEN1KMT2A | |
| SCHEMBL5994490 | 0.82 | HDAC1 (0.60) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1805930-A | Hydroxamic acids useful in the treatment of hyper-proliferative disorders | BAYER PHARMACEUTICALS CORP (US) | 2006-07-19 | — | — | CN | disclosed |