Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10145725 | 0.82 | TSHR (0.33) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL27978620 | 0.81 | TSHR (0.31) | TSHRMAPK1 | |
| SCHEMBL6135298 | 0.81 | TSHR (0.50) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL10936469 | 0.80 | HSD17B10 (0.38) | — | |
| SCHEMBL19592037 | 0.79 | TSHR (0.47) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL10869841 | 0.78 | TSHR (0.33) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL23734755 | 0.77 | TSHR (0.36) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL10938898 | 0.77 | TSHR (0.37) | TSHR | |
| SCHEMBL3634942 | 0.77 | TSHR (0.45) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL12191728 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100512884-C | Alkylamine as an antimicrobial agent in ophthalmic compositions | ADVANCED MEDICAL OPTICS INC (US) | 2009-07-15 | — | — | CN | disclosed |
| CN-1938053-A | Alkylamine as an antimicrobial agent in ophthalmic compositions | ADVANCED MEDICAL OPTICS INC (US) | 2007-03-28 | — | — | CN | disclosed |
| CN-1748024-A | Contact lens care compositions, methods of use and preparation which protect ocular tissue membrane integrity | ADVANCED MEDICAL OPTICS INC (US) | 2006-03-15 | — | — | CN | disclosed |
| CN-1732021-A | Multifunctional contact lens care compositions comprising propylene glycol or glycerol | ADVANCED MEDICAL OPTICS INC (US) | 2006-02-08 | — | — | CN | disclosed |