Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.59 |
| ▸ | OXER1 | Q8TDS5 | 5/20 | 0.59 |
| ▸ | PPARG | P37231 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.59 |
| ▸ | F7 | P08709 | 3/20 | 0.59 |
| ▸ | F3 | P13726 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | PPARD | Q03181 | 3/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18010751 | 1.00 | PPARA (0.86) | PPARAALDH1A1CYP19A1OXER1PPARG | |
| SCHEMBL18274958 | 1.00 | PPARA (0.86) | PPARAALDH1A1CYP19A1OXER1PPARG | |
| SCHEMBL18274959 | 1.00 | PPARA (0.86) | PPARAALDH1A1CYP19A1OXER1PPARG | |
| SCHEMBL18185410 | 0.98 | PPARA (0.83) | PPARAALDH1A1CYP19A1OXER1PPARG | |
| SCHEMBL27880745 | 0.97 | PPARA (0.81) | PPARAALDH1A1CYP19A1OXER1PPARG | |
| SCHEMBL18185471 | 0.97 | PPARA (0.81) | PPARAALDH1A1CYP19A1OXER1PPARG | |
| SCHEMBL27870751 | 0.97 | PPARA (0.81) | PPARAALDH1A1CYP19A1OXER1PPARG | |
| SCHEMBL18185511 | 0.97 | PPARA (0.81) | PPARAALDH1A1CYP19A1OXER1PPARG | |
| SCHEMBL18185416 | 0.97 | PPARA (0.81) | PPARAALDH1A1CYP19A1OXER1PPARG | |
| SCHEMBL14695785 | 0.96 | PPARA (0.80) | PPARAALDH1A1CYP19A1OXER1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104812379-A | A pharmaceutical composition | CHRYSALIS PHARMA AG | 2015-07-29 | — | — | CN | claimed |
| CN-101232867-A | Cosmetic and/or dermatological composition for prevention and/or treatment of sensitive or dry skin | OREAL (FR) | 2008-07-30 | — | — | CN | disclosed |
| CN-100349887-C | Substituted 4-aryl-4H-pyrrolo [2, 3-H ] chromenes and analogs, pharmaceutical compositions and uses thereof | CYTOVIA INC (US) | 2007-11-21 | — | — | CN | disclosed |
| CN-1668609-A | Substituted 4-aryl-4H-pyrrolo[2,3-H]chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA INC (US) | 2005-09-14 | — | — | CN | disclosed |