Ethylbenzene

Ethylbenzene

SCHEMBL27633722

CCc1ccccc1.CCc1ccccc1.CCc1ccccc1CC.c1ccccc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.78
ALDH1A1 P00352 1/20 0.46
GABRA1 P14867 2/20 0.46
GABRB2 P47870 2/20 0.46
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
CALM1 P0DP23 1/20 0.43
GAA P10253 1/20 0.42
MGLL Q99685 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylbenzene SCHEMBL11185461 1.00 TP53 (0.78) TP53ALDH1A1GABRA1GABRB2PPARG
Ethylbenzene SCHEMBL3227891 1.00 TP53 (0.78) TP53ALDH1A1GABRA1GABRB2PPARG
Ethylbenzene SCHEMBL25402571 0.97 TP53 (0.74) TP53ALDH1A1GABRA1GABRB2PPARG
Ethylbenzene SCHEMBL4822176 0.93 TP53 (0.67) TP53ALDH1A1GABRA1GABRB2PPARG
SCHEMBL25425761 0.92 TP53 (0.63) TP53ALDH1A1GABRA1GABRB2MGLL
Ethylbenzene SCHEMBL27524247 0.89 TP53 (0.61) TP53ALDH1A1GABRA1GABRB2PPARG
Benzene SCHEMBL11603070 0.88 TP53 (0.56) TP53GABRA1GABRB2MGLL
Ethylbenzene SCHEMBL11223212 0.88 TP53 (1.00) TP53ALDH1A1CALM1CYP1A2CYP2A6
Ethylbenzene SCHEMBL1332452 0.88
Benzene SCHEMBL3122858 0.88 TP53 (0.56) TP53GABRA1GABRB2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1721377-A Process for preparing p-xylene SINOPEC CORP (CN) 2006-01-18 CN disclosed