Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28754207 | 0.91 | PROKR1 (0.49) | PROKR1ALDH1A1NPC1GAACHRM4 | |
| SCHEMBL27616088 | 0.91 | PROKR1 (0.49) | PROKR1ALDH1A1NPC1GAACHRM4 | |
| SCHEMBL27616094 | 0.91 | PROKR1 (0.49) | PROKR1ALDH1A1NPC1GAACHRM4 | |
| SCHEMBL4028701 | 0.90 | PROKR1 (0.49) | PROKR1ALDH1A1NPC1GAACHRM4 | |
| SCHEMBL4032748 | 0.90 | PROKR1 (0.49) | PROKR1ALDH1A1NPC1GAACHRM4 | |
| SCHEMBL4029357 | 0.90 | PROKR1 (0.49) | PROKR1ALDH1A1NPC1GAACHRM4 | |
| SCHEMBL4030709 | 0.89 | PROKR1 (0.49) | PROKR1ALDH1A1NPC1GAACHRM4 | |
| SCHEMBL4031382 | 0.89 | PROKR1 (0.49) | PROKR1ALDH1A1NPC1GAACHRM4 | |
| SCHEMBL4033034 | 0.89 | PROKR1 (0.49) | PROKR1ALDH1A1NPC1GAACHRM4 | |
| SCHEMBL27727437 | 0.89 | PROKR1 (0.49) | PROKR1ALDH1A1NPC1GAACHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1717389-A | Phenyl substituted piperidine compounds for use as PPAR activators | PFIZER PROD INC (US) | 2006-01-04 | — | — | CN | disclosed |