Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | GART | P22102 | 2/20 | 0.34 |
| ▸ | FOLR2 | P14207 | 1/20 | 0.34 |
| ▸ | FOLR1 | P15328 | 1/20 | 0.34 |
| ▸ | SLC19A1 | P41440 | 1/20 | 0.34 |
| ▸ | SLC46A1 | Q96NT5 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1243385 | 1.00 | MEN1 (0.45) | MEN1GAAKMT2APIN1TYMS | |
| SCHEMBL1242697 | 0.85 | MEN1 (0.51) | MEN1GAAKMT2AFOXO1KDM4E | |
| SCHEMBL27635118 | 0.84 | MEN1 (0.54) | MEN1GAAKMT2APIN1TYMS | |
| SCHEMBL1242497 | 0.84 | MEN1 (0.54) | MEN1GAAKMT2APIN1TYMS | |
| SCHEMBL1243905 | 0.79 | MEN1 (0.47) | MEN1GAAKMT2AFOXO1KDM4E | |
| SCHEMBL27656155 | 0.78 | MEN1 (0.53) | MEN1GAAKMT2APIN1EPHX2 | |
| SCHEMBL1243864 | 0.78 | MEN1 (0.53) | MEN1GAAKMT2APIN1EPHX2 | |
| SCHEMBL261932 | 0.73 | MEN1 (0.52) | MEN1GAAKMT2APIN1FOXO1 | |
| SCHEMBL1243323 | 0.72 | MEN1 (0.75) | MEN1GAAKMT2AFOXO1KDM4E | |
| SCHEMBL1242841 | 0.72 | MEN1 (0.58) | MEN1GAAKMT2AFOXO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100471842-C | Carbostyril derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-03-25 | — | — | CN | claimed |
| CN-1826321-A | Quinolone derivative or its salt | YAMANOUCHI PHARMA CO LTD (JP) | 2006-08-30 | — | — | CN | claimed |
| CN-100471842-C | Carbostyril derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-03-25 | — | — | CN | disclosed |
| CN-1826321-A | Quinolone derivative or its salt | YAMANOUCHI PHARMA CO LTD (JP) | 2006-08-30 | — | — | CN | disclosed |