Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2644170 | 0.89 | KCNH2 (0.71) | KCNH2GCK | |
| SCHEMBL2644172 | 0.89 | KCNH2 (0.71) | KCNH2GCK | |
| SCHEMBL2644622 | 0.88 | KCNH2 (0.73) | KCNH2GCK | |
| SCHEMBL2644619 | 0.88 | KCNH2 (0.73) | KCNH2GCK | |
| SCHEMBL2644475 | 0.86 | KCNH2 (0.75) | KCNH2GCK | |
| SCHEMBL2644472 | 0.86 | KCNH2 (0.75) | KCNH2GCK | |
| SCHEMBL2664479 | 0.86 | KCNH2 (0.75) | KCNH2GCK | |
| SCHEMBL2644341 | 0.86 | KCNH2 (0.75) | KCNH2GCK | |
| SCHEMBL2645648 | 0.86 | KCNH2 (0.75) | KCNH2GCK | |
| SCHEMBL2644112 | 0.84 | KCNH2 (0.71) | KCNH2GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100469770-C | 5-substituted-pyrazine or -pyridine glucokinase activators | HOFFMANN LA ROCHE (CH) | 2009-03-18 | — | — | CN | disclosed |
| CN-1726197-A | 5-substituted-pyrazine or -pyridine glucokinase activators | HOFFMANN LA ROCHE (CH) | 2006-01-25 | — | — | CN | disclosed |