Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CTSE | P14091 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1141929 | 0.90 | ELANE (0.33) | ELANEGPR119 | |
| SCHEMBL1141692 | 0.88 | ELANE (0.32) | ELANEGPR119 | |
| SCHEMBL1141482 | 0.78 | AKT1 (0.38) | ELANEROCK2PIK3CAMTORPIK3CG | |
| SCHEMBL1141485 | 0.78 | ELANE (0.31) | ELANE | |
| SCHEMBL11911441 | 0.77 | MAP2K4 (0.40) | ELANEROCK2AURKB | |
| SCHEMBL27637417 | 0.73 | MAP2K4 (0.38) | ELANEROCK2AURKB | |
| SCHEMBL27637471 | 0.72 | MAP2K4 (0.33) | ELANEROCK2PIK3CAMTORPIK3CG | |
| SCHEMBL1141597 | 0.72 | MAP2K4 (0.36) | ELANEGPR119ROCK2PIK3CAMTOR | |
| SCHEMBL1141491 | 0.71 | GRM2 (0.43) | ROCK2ATRAURKB | |
| SCHEMBL27637644 | 0.71 | MAP2K4 (0.36) | ELANEROCK2AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1863779-B | indazole derivatives | UBE INDUSTRIES | 2010-05-05 | — | — | CN | disclosed |
| CN-1863779-A | Novel indazole derivative | UBE INDUSTRIES (JP) | 2006-11-15 | — | — | CN | disclosed |