Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 15/20 | 0.73 |
| ▸ | ESR2 | Q92731 | 15/20 | 0.73 |
| ▸ | ESRRB | O95718 | 2/20 | 0.52 |
| ▸ | ESRRA | P11474 | 2/20 | 0.52 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27659332 | 0.86 | ESR2 (0.71) | ESR1ESR2ESRRBESRRA | |
| SCHEMBL27659352 | 0.85 | ESR1 (0.53) | ESR1ESR2ESRRBESRRAALOX5AP | |
| SCHEMBL27659450 | 0.84 | ESR1 (0.77) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL3926403 | 0.84 | ESR1 (1.00) | ESR1ESR2ESRRBESRRA | |
| SCHEMBL27659356 | 0.83 | ESR1 (0.53) | ESR1ESR2ESRRBESRRAALOX5AP | |
| SCHEMBL27659335 | 0.82 | ESR1 (0.70) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27638485 | 0.82 | ESR2 (0.71) | ESR1ESR2ESRRBESRRAALOX5AP | |
| SCHEMBL27638498 | 0.82 | ESR2 (0.71) | ESR1ESR2ESRRBESRRAALOX5AP | |
| SCHEMBL28760330 | 0.81 | ESR1 (0.57) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27638495 | 0.81 | ESR1 (0.67) | ESR1ESR2ALOX5APFEN1QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1823046-A | Phenyl quinolines and their use as estrogen receptor modulators | WYETH CORP (US) | 2006-08-23 | — | — | CN | claimed |
| CN-1823046-A | Phenyl quinolines and their use as estrogen receptor modulators | WYETH CORP (US) | 2006-08-23 | — | — | CN | disclosed |