Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.73 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 4/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.43 |
| ▸ | FEN1 | P39748 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27659336 | 0.86 | ESR1 (0.72) | ESR1ESR2KMT2ADHODHKDM4E | |
| SCHEMBL27659450 | 0.86 | ESR1 (0.77) | ESR1ESR2MEN1KMT2AALOX5AP | |
| SCHEMBL3921639 | 0.85 | ESR1 (1.00) | ESR1ESR2MEN1KMT2ADHODH | |
| SCHEMBL27659335 | 0.84 | ESR1 (0.70) | ESR1ESR2MEN1KMT2ADHODH | |
| SCHEMBL27638496 | 0.83 | ESR1 (0.73) | ESR1ESR2DHODHALOX5APFEN1 | |
| SCHEMBL27638488 | 0.82 | ESR1 (0.67) | ESR1ESR2MEN1KMT2ADHODH | |
| SCHEMBL27638495 | 0.82 | ESR1 (0.67) | ESR1ESR2MEN1KMT2ADHODH | |
| SCHEMBL27638498 | 0.81 | ESR2 (0.71) | ESR1ESR2ALOX5APFEN1 | |
| SCHEMBL27638485 | 0.81 | ESR2 (0.71) | ESR1ESR2MEN1KMT2AALOX5AP | |
| SCHEMBL27638541 | 0.81 | ESR2 (0.62) | ESR1ESR2MEN1KMT2AALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1823046-A | Phenyl quinolines and their use as estrogen receptor modulators | WYETH CORP (US) | 2006-08-23 | — | — | CN | claimed |
| CN-1823046-A | Phenyl quinolines and their use as estrogen receptor modulators | WYETH CORP (US) | 2006-08-23 | — | — | CN | disclosed |