Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | MMP12 | P39900 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL18393376 | 0.91 | — | — | |
| Lactic Acid SCHEMBL1450479 | 0.88 | TP53 (0.73) | TP53KDM4ECA2PTGS1MMP12 | |
| Diacetamide SCHEMBL29112014 | 0.82 | TP53 (0.65) | TP53KDM4ECA2PTGS1MMP12 | |
| Lactic Acid SCHEMBL27710699 | 0.81 | TP53 (0.85) | TP53ALDH1A1TSHRSLC7A5FFAR3 | |
| Lactic Acid SCHEMBL6264768 | 0.81 | TP53 (0.85) | TP53ALDH1A1TSHRSLC7A5FFAR3 | |
| Lactic Acid SCHEMBL8948591 | 0.81 | TP53 (0.85) | TP53ALDH1A1TSHRSLC7A5FFAR3 | |
| Lactic Acid SCHEMBL1018571 | 0.81 | TP53 (0.85) | TP53ALDH1A1TSHRSLC7A5FFAR3 | |
| Lactic Acid SCHEMBL6943476 | 0.81 | TP53 (0.85) | TP53ALDH1A1TSHRSLC7A5FFAR3 | |
| Lactic Acid SCHEMBL7778386 | 0.81 | TP53 (0.85) | TP53ALDH1A1TSHRSLC7A5FFAR3 | |
| Lactic Acid SCHEMBL5189465 | 0.80 | TP53 (1.00) | TP53ALDH1A1THRBRECQLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105125484-A | Painless doxycycline injection and preparation method thereof | HUNAN TAIGU BIOLOG VETERINARY DRUG CO LTD | 2015-12-09 | — | — | CN | claimed |
| CN-1857222-B | Submicron docetaxel emulsion for intravenous injection and its preparing process | CHINA MEDICINE RES & DEV CT CO LTD | 2010-05-12 | — | — | CN | claimed |
| CN-1857222-A | Submicron docetaxel emulsion for intravenous injection and its preparing process | CHINA MEDICINE RES DEV CT CO L (CN) | 2006-11-08 | — | — | CN | claimed |
| CN-105125484-A | Painless doxycycline injection and preparation method thereof | HUNAN TAIGU BIOLOG VETERINARY DRUG CO LTD | 2015-12-09 | — | — | CN | disclosed |
| CN-1857222-B | Submicron docetaxel emulsion for intravenous injection and its preparing process | CHINA MEDICINE RES & DEV CT CO LTD | 2010-05-12 | — | — | CN | disclosed |
| CN-1857222-A | Submicron docetaxel emulsion for intravenous injection and its preparing process | CHINA MEDICINE RES DEV CT CO L (CN) | 2006-11-08 | — | — | CN | disclosed |