Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 11/20 | 0.64 |
| ▸ | KIT | P10721 | 9/20 | 0.64 |
| ▸ | ABL1 | P00519 | 16/20 | 0.60 |
| ▸ | BCR | P11274 | 14/20 | 0.60 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.60 |
| ▸ | SRC | P12931 | 2/20 | 0.60 |
| ▸ | SYK | P43405 | 2/20 | 0.60 |
| ▸ | EGFR | P00533 | 2/20 | 0.60 |
| ▸ | PLK4 | O00444 | 1/20 | 0.60 |
| ▸ | DDX3X | O00571 | 1/20 | 0.60 |
| ▸ | GAK | O14976 | 1/20 | 0.60 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.60 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ALB | P02768 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5067293 | 0.91 | PDGFRA (0.75) | PDGFRAKITABL1BCRPDGFRB | |
| SCHEMBL27744872 | 0.85 | ABL1 (0.82) | PDGFRAKITABL1BCRPDGFRB | |
| SCHEMBL5201739 | 0.85 | PDGFRA (0.65) | PDGFRAKITABL1BCRPDGFRB | |
| SCHEMBL27781983 | 0.82 | PDGFRA (0.71) | PDGFRAKITABL1BCRPDGFRB | |
| SCHEMBL25281830 | 0.79 | PDGFRA (1.00) | PDGFRAKITABL1BCRPDGFRB | |
| SCHEMBL29628979 | 0.79 | PDGFRA (1.00) | PDGFRAKITABL1BCRPDGFRB | |
| SCHEMBL3052393 | 0.78 | ABL1 (0.83) | PDGFRAKITABL1BCRPDGFRB | |
| SCHEMBL5201838 | 0.78 | PDGFRA (0.55) | PDGFRAKITABL1BCRPDGFRB | |
| SCHEMBL14375828 | 0.76 | PDGFRA (0.75) | PDGFRAKITABL1BCRPDGFRB | |
| SCHEMBL12901010 | 0.76 | ABL1 (0.89) | PDGFRAKITABL1BCRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1756849-A | Modulation of protein functionality | DECIPHERA PHARMACEUTICALS LLC (US) | 2006-04-05 | — | — | CN | disclosed |