Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 1.00 |
| ▸ | MAPK13 | O15264 | 11/20 | 1.00 |
| ▸ | MAPK12 | P53778 | 11/20 | 1.00 |
| ▸ | MAPK11 | Q15759 | 11/20 | 1.00 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.82 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.82 |
| ▸ | SRC | P12931 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28942120 | 0.92 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL3194134 | 0.92 | MAPK14 (0.84) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL12245421 | 0.91 | MAPK14 (0.88) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL12245411 | 0.90 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2079824 | 0.90 | MAPK14 (0.81) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL3300823 | 0.89 | MAPK14 (0.80) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL3192015 | 0.89 | MAPK14 (0.82) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL13857353 | 0.89 | MAPK14 (0.80) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL3292974 | 0.89 | MAPK14 (0.80) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL12245434 | 0.88 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1756849-A | Modulation of protein functionality | DECIPHERA PHARMACEUTICALS LLC (US) | 2006-04-05 | — | — | CN | disclosed |