Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 7/20 | 0.57 |
| ▸ | RHOC | P08134 | 1/20 | 0.53 |
| ▸ | RHOA | P61586 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vgx-1027 SCHEMBL1404343 | 0.81 | MIF (0.78) | MIFITGB3ITGA2B | |
| Vgx-1027 SCHEMBL1414048 | 0.81 | MIF (0.78) | MIFITGB3ITGA2B | |
| SCHEMBL27482944 | 0.81 | MIF (0.61) | MIFF10F2ITGB3ITGA2B | |
| SCHEMBL746606 | 0.81 | POLB (0.57) | ATMF10HTT | |
| SCHEMBL2662779 | 0.77 | MIF (0.56) | MIF | |
| SCHEMBL11378726 | 0.77 | MIF (0.45) | MIFRHOCRHOAATMF10 | |
| SCHEMBL12209194 | 0.75 | F10 (0.44) | ATMF10 | |
| SCHEMBL743565 | 0.75 | MIF (0.60) | MIFATMF10HTT | |
| SCHEMBL27640963 | 0.75 | F10 (0.45) | MIFRHOCRHOAATMF10 | |
| SCHEMBL11394124 | 0.74 | F10 (0.45) | ATMF10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1741994-A | 3-aminopyrrolidine derivatives as modulators of chemokine receptors | INCYTE CORP (US) | 2006-03-01 | — | — | CN | disclosed |