Biphenyl

Biphenyl

SCHEMBL27642147

CCC(=O)O.CCC(=O)O.CO.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.61
MAPT P10636 4/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
LMNA P02545 2/20 0.54
ABCC4 O15439 1/20 0.54
GAA P10253 1/20 0.54
TSHR P16473 1/20 0.54
PTGS1 P23219 1/20 0.54
HTT P42858 1/20 0.54
FFAR3 O14843 1/20 0.53
HPGD P15428 2/20 0.52
ALDH1A1 P00352 4/20 0.50
FFAR1 O14842 2/20 0.50
CYP1A2 P05177 1/20 0.48
RAB9A P51151 1/20 0.48
HIF1A Q16665 1/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
KDM4E B2RXH2 2/20 0.47
AGTR1 P30556 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27593503 1.00 SMN1; SMN2 (0.61) SMN1; SMN2MAPTL3MBTL1LMNAABCC4
Biphenyl SCHEMBL1050110 0.97 SMN1; SMN2 (0.64) SMN1; SMN2MAPTL3MBTL1LMNAABCC4
Biphenyl SCHEMBL15333645 0.97 SMN1; SMN2 (0.64) SMN1; SMN2MAPTL3MBTL1LMNAABCC4
Biphenyl SCHEMBL27481591 0.95 SMN1; SMN2 (0.61) SMN1; SMN2MAPTL3MBTL1LMNAABCC4
Biphenyl SCHEMBL27339135 0.95 SMN1; SMN2 (0.61) SMN1; SMN2MAPTL3MBTL1LMNAABCC4
Biphenyl SCHEMBL29174569 0.92 SMN1; SMN2 (0.59) SMN1; SMN2MAPTL3MBTL1LMNAABCC4
Biphenyl SCHEMBL7178645 0.92 SMN1; SMN2 (0.59) SMN1; SMN2MAPTL3MBTL1LMNAABCC4
Propionic Acid SCHEMBL1932778 0.86 FFAR3 (0.62) SMN1; SMN2MAPTL3MBTL1LMNAABCC4
Propionic Acid SCHEMBL29662033 0.85 MAPT (0.52) SMN1; SMN2MAPTL3MBTL1LMNAABCC4
Biphenyl SCHEMBL22163814 0.84 MAPT (0.61) SMN1; SMN2MAPTL3MBTL1LMNAABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1743346-A Catalyst component for olefinic polymerization and its catalyst CHINA PETROCHEMICAL CORP (CN) 2006-03-08 CN disclosed
CN-1743348-A Catalyst component for olefinic polymerization and its catalyst CHINA PETROCHEMICAL CORP (CN) 2006-03-08 CN disclosed