SCHEMBL2764293

SCHEMBL2764293

Cc1nn(C)c(Oc2ccccc2)c1C=NOCc1ccc(C(=O)O)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.43
ALDH1A1 P00352 4/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
SRD5A2 P31213 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPT P10636 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
NR4A1 P22736 1/20 0.39
NR4A2 P43354 1/20 0.39
NR4A3 Q92570 1/20 0.39
TP53 P04637 1/20 0.39
NPY1R P25929 1/20 0.39
NPY2R P49146 1/20 0.39
HTT P42858 1/20 0.38
LMNA P02545 1/20 0.38
PTGES O14684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2832660 1.00 GAA (0.43) GAAALDH1A1KMT2ASMN1; SMN2SRD5A2
SCHEMBL9673489 0.99 GAA (0.42) GAAALDH1A1KMT2ASMN1; SMN2SRD5A2
SCHEMBL9672883 0.91 GAA (0.49) GAAALDH1A1KMT2ASMN1; SMN2KDM4E
SCHEMBL9672888 0.91 GAA (0.49) GAAALDH1A1KMT2ASMN1; SMN2KDM4E
SCHEMBL9673480 0.91 GAA (0.43) GAAALDH1A1KMT2ASMN1; SMN2CYP1A2
SCHEMBL9673165 0.90 SMN1; SMN2 (0.45) GAAALDH1A1KMT2ASMN1; SMN2CYP1A2
SCHEMBL9673017 0.90 GAA (0.41) GAAALDH1A1KMT2ASMN1; SMN2CYP1A2
SCHEMBL9674943 0.90 GAA (0.41) GAAALDH1A1KMT2ASMN1; SMN2CYP1A2
SCHEMBL9673010 0.90 GAA (0.41) GAAALDH1A1KMT2ASMN1; SMN2CYP1A2
SCHEMBL9672447 0.90 GAA (0.39) GAAALDH1A1KMT2ASMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002080675-A9 TREATED PLANT SEEDS WITH CONTROLLED RELEASE OF ACTIVE AGENTS MONSANTO TECHNOLOGY LLC (US) 2004-05-06 WO claimed
EP-1370136-A1 TREATED PLANT SEEDS WITH CONTROLLED RELEASE OF ACTIVE AGENTS Monsanto Technology LLC (US) 2003-12-17 EP claimed
WO-2002080675-A1 TREATED PLANT SEEDS WITH CONTROLLED RELEASE OF ACTIVE AGENTS MONSANTO TECHNOLOGY, LLC (US) 2002-10-17 WO claimed
JP-9110617-A None JP disclosed
US-20220264897-A1 COMPOSITIONS AND METHODS RELATING TO INSECTICIDES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2022-08-25 US disclosed
US-20220174963-A1 COMPOSITIONS AND METHODS RELATING TO INSECTICIDES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2022-06-09 US disclosed
WO-2021041278-A2 COMPOSITIONS AND METHODS RELATING TO INSECTICIDES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) 2021-03-04 WO disclosed
WO-2020023368-A1 POGOSTONE DERIVATIVES AND METHODS OF USING THE SAME Hamyard Associates LLC (US) 2020-01-30 WO disclosed
US-9163110-B2 Granule coated with urethane resin SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-20 US disclosed
US-8932613-B2 Ectoparasite control method E I DU PONT DE NEMOURS AND COMPANY (US) 2015-01-13 US disclosed
US-20100210601-A1 FLEA CONTROL METHOD E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-19 US disclosed
WO-1997028112-A1 DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-07 WO disclosed
WO-1997027173-A2 DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-31 WO disclosed
EP-0785923-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-07-30 EP disclosed
JP-H09110617-A COMPOSITION FOR PREVENTING PINES FROM WITHERING SANKYO CO LTD 1997-04-28 JP disclosed
WO-1996033160-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-24 WO disclosed
WO-1996011909-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-25 WO disclosed
EP-0234045-B1 A PYRAZOLE OXIME DERIVATIVE AND ITS PRODUCTION AND USE NIHON NOHYAKU CO., LTD. (JP) 1992-09-02 EP disclosed
US-4843068-A INSECTICIDES, MITICIDES, FUNGICIDES NIHON NOHYAKU CO., LTD. (JP) 1989-06-27 US disclosed
EP-0234045-A2 A pyrazole oxime derivative and its production and use NIHON NOHYAKU CO., LTD. (JP) 1987-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210601-A1 FLEA CONTROL METHOD SCN1B, SCN1A, NOX1 GAA 2940/4885ALDH1A1 597/4885KMT2A 1748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.