⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277142 | 0.83 | — | — | |
| SCHEMBL8897932 | 0.79 | KDM4C (0.47) | — | |
| SCHEMBL8158685 | 0.79 | KDM4C (0.47) | — | |
| SCHEMBL7769410 | 0.78 | — | — | |
| SCHEMBL1030135 | 0.78 | — | — | |
| SCHEMBL1889075 | 0.77 | — | — | |
| SCHEMBL276694 | 0.76 | — | — | |
| SCHEMBL110531 | 0.75 | CA1 (0.60) | — | |
| SCHEMBL7615209 | 0.75 | CA1 (0.68) | — | |
| SCHEMBL7312905 | 0.74 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 397 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269737-A1 | 7-(Piperazine-1-Ymethyl)-1H-Indole-2-Carboxylic Acid (Phenyl)-Amide Derivatives and Allied Compounds as P38 Map Kinase Inhibitors for the Treatment of Respiratory Diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-03 | — | — | US | claimed |
| EP-2323980-A1 | 7-(PIPERAZINE-1-YMETHYL)-1H-INDOLE-2-CARBOXYLIC ACID (PHENYL)-AMIDE DERIVATIVES AND ALLIED COMPOUNDS AS P38 MAP KINASE INHIBITORS FOR THE TREATMENT OF RESPIRATORY DISEASES | Boehringer Ingelheim International GmbH (DE) | 2011-05-25 | — | — | EP | claimed |
| WO-2010026096-A1 | 7-(PIPERAZINE-1-YMETHYL)-1H-INDOLE-2-CARBOXYLIC ACID (PHENYL)-AMIDE DERIVATIVES AND ALLIED COMPOUNDS AS P38 MAP KINASE INHIBITORS FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | claimed |
| US-20060058553-A1 | Novel bicyclic hydroxamates as inhibitors of histone deacetylase | AXYS PHARMACEUTICALS, INC. (US) | 2006-03-16 | — | — | US | claimed |
| EP-1472216-A2 | NOVEL BICYCLIC HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | Axys Pharmaceuticals (US) | 2004-11-03 | — | — | EP | claimed |
| WO-2003066579-A2 | NOVEL BICYCLIC HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | AXYS PHARMACEUTICALS (US) | 2003-08-14 | — | — | WO | claimed |
| US-6414012-B1 | CARDIOVASCULAR DISORDERS; ANTICHOLESTEROL AGENTS | SANKYO COMPANY, LIMITED (JP) | 2002-07-02 | — | — | US | claimed |
| US-6127403-A | AN ENZYME INHIBITOR FOR TREATING ARTERIOSCLEROTIC LESIONS OF ARTERIOSCLEROSIS, HYPERLIPEMIA AND DIABETES, AS WELL AS ISCHEMIC DISEASES OF BRAIN, HEART | SANKYO COMPANY, LTD. (JP) | 2000-10-03 | — | — | US | claimed |
| CN-112280567-B | Composition comprising compound functioning as dichromatic pigment | 住友化学株式会社 | 2024-06-25 | — | — | CN | disclosed |
| WO-2024128000-A1 | ISOPOLYOXOTUNGSTATE SALT COMPOUND, SOLVATE THEREOF OR MIXTURE OF SAID COMPOUND AND SOLVATE, AND METHOD FOR PRODUCING SAID COMPOUND, SOLVATE OR MIXTURE | 東京応化工業株式会社 | 2024-06-20 | — | — | WO | disclosed |
| CN-114026199-B | Polarized light emitting film, polarized light emitting panel and display device containing water-soluble coumarin compound or salt thereof | 日本化药株式会社 | 2023-12-26 | — | — | CN | disclosed |
| EP-4269119-A1 | COLOR DEVELOPER, HEAT-SENSITIVE RECORDING MATERIAL, AND COATING MATERIAL FOR HEAT-SENSITIVE RECORDING LAYERS | Sanko Co., Ltd. (JP) | 2023-11-01 | — | — | EP | disclosed |
| CN-116813979-A | Nucleating agent, synthetic resin composition containing same, and molded article thereof | 株式会社ADEKA | 2023-09-29 | — | — | CN | disclosed |
| CN-110740991-B | Novel biphenyl compound or salt thereof | 大鹏药品工业株式会社 | 2023-07-04 | — | — | CN | disclosed |
| EP-0387201-B1 | Mixture of dyestuffs and their use | CIBA GEIGY AG (CH) | 1994-02-02 | — | — | EP | disclosed |
| US-5216171-A | Nitrification inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| US-5131919-A | Trichromic dyeing or printing | CIBA-GEIGY CORPORATION (US) | 1992-07-21 | — | — | US | disclosed |
| EP-0453883-A2 | 2-amino-4-trichloropyridine derivatives | BASF Aktiengesellschaft (DE) | 1991-10-30 | — | — | EP | disclosed |
| EP-0414058-A2 | Carboxylic acid derivatives | BASF Aktiengesellschaft (DE) | 1991-02-27 | — | — | EP | disclosed |
| EP-0387201-A1 | Mixture of dyestuffs and their use | CIBA-GEIGY AG (CH) | 1990-09-12 | — | — | EP | disclosed |