⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6843504 | 0.97 | HDAC8 (0.43) | — | |
| Hydrochloric Acid SCHEMBL15569913 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL6079983 | 0.97 | HDAC8 (0.43) | — | |
| Methane SCHEMBL4360583 | 0.97 | — | — | |
| Methyl Alcohol SCHEMBL28185437 | 0.65 | — | — | |
| SCHEMBL5179594 | 0.64 | ESR1 (0.50) | — | |
| SCHEMBL5752803 | 0.63 | KMT2A (0.47) | — | |
| SCHEMBL17591495 | 0.63 | — | — | |
| SCHEMBL8866018 | 0.63 | HDAC8 (0.40) | — | |
| SCHEMBL2391653 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020534-A1 | COMPOUNDS AND THEIR USES AS MIF INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-02-23 | — | — | WO | claimed |
| CN-108047199-B | A kind of thiazole spirocyclopropane skeleton object and its crystal and preparation method | 中国医药集团总公司四川抗菌素工业研究所 | 2019-09-03 | — | — | CN | claimed |
| CN-108697709-A | Methods for treating huntington's disease | PTC医疗公司 | 2018-10-23 | — | — | CN | claimed |
| CN-108047199-A | A kind of thiazole spirocyclopropane skeleton object and its crystal and preparation method | 中国医药集团总公司四川抗菌素工业研究所 | 2018-05-18 | — | — | CN | claimed |
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | claimed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | claimed |
| CN-112789298-B | Polymer and use thereof | 日产化学株式会社 | 2024-04-30 | — | — | CN | disclosed |
| CN-110869360-B | Phenylacetamides as ROCK inhibitors | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-117126151-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-117126152-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-117069713-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117069712-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117024420-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| WO-2005003140-A1 | 4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-01-13 | — | — | WO | disclosed |
| US-20050004161-A1 | 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents | AGOURON PHARMACEUTICALS, INC. | 2005-01-06 | — | — | US | disclosed |
| CN-1554647-A | Process for synthesizing ritonavir | 厦门大学 | 2004-12-15 | — | — | CN | disclosed |
| WO-1998045279-A1 | PREPARATION OF THIAZOLES USING 1,3-DIHALOPROPENES | REILLY INDUSTRIES, INC. (US) | 1998-10-15 | — | — | WO | disclosed |
| US-4665066-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1987-05-12 | — | — | US | disclosed |
| US-4528291-A | 2-(4'-Pyridinyl)-thiazole compounds and their use in increasing cardiac contractility | SCHERING CORPORATION (US) | 1985-07-09 | — | — | US | disclosed |
| US-4242495-A | COATINGS, MOLDINGS, FOAMS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-12-30 | — | — | US | disclosed |