Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8129682 | 0.88 | SLC1A1 (0.64) | SLC1A1SLC1A3SLC1A2GRIK1SLC7A5 | |
| SCHEMBL17978113 | 0.84 | SLC7A5 (0.45) | SLC7A5PPARGPPARACYP1A2KIF11 | |
| SCHEMBL17978114 | 0.84 | SLC7A5 (0.45) | SLC7A5PPARGPPARACYP1A2KIF11 | |
| SCHEMBL2262934 | 0.83 | SLC1A1 (0.73) | SLC1A1SLC1A3SLC1A2GRIK1GRIK2 | |
| SCHEMBL13726229 | 0.81 | SLC7A5 (0.46) | SLC1A1SLC1A3SLC1A2SLC7A5 | |
| SCHEMBL12656116 | 0.81 | SLC7A5 (0.46) | SLC1A1SLC1A3SLC1A2SLC7A5 | |
| SCHEMBL13726226 | 0.81 | SLC7A5 (0.46) | SLC1A1SLC1A3SLC1A2SLC7A5 | |
| SCHEMBL1519895 | 0.80 | SLC7A5 (0.41) | SLC7A5PPARGPPARACYP1A2KIF11 | |
| SCHEMBL7436701 | 0.80 | CYP1A2 (0.57) | SLC1A1SLC1A3SLC1A2PPARGPPARA | |
| SCHEMBL7436695 | 0.80 | CYP1A2 (0.57) | SLC1A1SLC1A3SLC1A2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1882347-A | AKT protein kinase inhibitors | ARRAY BIOPHARMA INC (US) | 2006-12-20 | — | — | CN | disclosed |