Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 15/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 18/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 8/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.52 |
| ▸ | GRK5 | P34947 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5851485 | 0.91 | S1PR1 (0.46) | S1PR5S1PR1S1PR4S1PR3GRK5 | |
| SCHEMBL27624823 | 0.83 | S1PR5 (0.55) | S1PR5S1PR1S1PR4S1PR3 | |
| SCHEMBL4664486 | 0.80 | S1PR5 (0.56) | S1PR5S1PR1S1PR4S1PR3GRK5 | |
| SCHEMBL4662867 | 0.80 | S1PR5 (0.55) | S1PR5S1PR1S1PR4S1PR3GRK5 | |
| SCHEMBL2638547 | 0.75 | S1PR1 (0.53) | S1PR5S1PR1S1PR4S1PR3GRK5 | |
| SCHEMBL13233711 | 0.75 | S1PR1 (0.54) | S1PR5S1PR1S1PR4S1PR3 | |
| SCHEMBL2941432 | 0.75 | S1PR1 (0.61) | S1PR5S1PR1S1PR4S1PR3 | |
| SCHEMBL1567838 | 0.74 | S1PR1 (0.63) | S1PR5S1PR1S1PR4S1PR3PDGFRA | |
| SCHEMBL12631603 | 0.74 | S1PR1 (0.63) | S1PR5S1PR1S1PR4S1PR3PDGFRA | |
| SCHEMBL1567840 | 0.74 | S1PR1 (0.63) | S1PR5S1PR1S1PR4S1PR3PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1787817-B | Immunosuppressant compounds and compositions | IRM LLC | 2011-09-07 | — | — | CN | claimed |
| CN-1787817-A | Immunosuppressant compounds and compositions | IRM LLC (BM) | 2006-06-14 | — | — | CN | claimed |
| CN-1787817-B | Immunosuppressant compounds and compositions | IRM LLC | 2011-09-07 | — | — | CN | disclosed |
| CN-1787817-A | Immunosuppressant compounds and compositions | IRM LLC (BM) | 2006-06-14 | — | — | CN | disclosed |