Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KLK1 | P06870 | 4/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758015 | 0.90 | KDM4E (0.51) | KLKB1HPGDKDM4EALDH1A1LSS | |
| SCHEMBL6212966 | 0.83 | RXFP1 (0.50) | KLKB1HPGDKDM4EALDH1A1PKM | |
| SCHEMBL27624384 | 0.83 | KLKB1 (0.49) | KLKB1HPGDKDM4EALDH1A1PKM | |
| SCHEMBL5758879 | 0.81 | MAPT (0.52) | KLKB1HPGDKDM4EALDH1A1LSS | |
| SCHEMBL27644966 | 0.79 | HPGD (0.50) | HPGDKDM4EALDH1A1LSSHSD17B10 | |
| SCHEMBL5758889 | 0.79 | CNR1 (0.50) | HPGDALDH1A1TP53ELANEMAPT | |
| SCHEMBL5759600 | 0.79 | KDM4E (0.55) | KLKB1HPGDKDM4EALDH1A1LSS | |
| SCHEMBL5757304 | 0.78 | TP53 (0.63) | KLKB1HPGDKDM4EALDH1A1LSS | |
| SCHEMBL27624403 | 0.77 | KLKB1 (0.52) | KLKB1HPGDKDM4EALDH1A1LSS | |
| SCHEMBL5757268 | 0.77 | TP53 (0.57) | HPGDKDM4EALDH1A1LSSHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1711243-A | 2-pyridone derivatives as inhibitors of neutrophil elastase | ASTRAZENECA AB (SE) | 2005-12-21 | — | — | CN | disclosed |