Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.67 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4446637 | 0.86 | PTGER4 (0.76) | PTGER4PTGER2KMT2A | |
| SCHEMBL4445206 | 0.86 | PTGER4 (0.76) | PTGER4PTGER2GLAHPGDS | |
| SCHEMBL4450921 | 0.85 | PTGER4 (0.74) | PTGER4PTGER2KMT2A | |
| SCHEMBL4450541 | 0.84 | PTGER4 (0.73) | PTGER4PTGER2KMT2A | |
| SCHEMBL4446742 | 0.83 | PTGER4 (0.72) | PTGER4PTGER2HDAC1KMT2A | |
| SCHEMBL13934834 | 0.83 | PTGER4 (0.88) | PTGER4PTGER2 | |
| SCHEMBL4450937 | 0.81 | PTGER4 (1.00) | PTGER4PTGER2KMT2A | |
| SCHEMBL4448231 | 0.79 | PTGER4 (0.85) | PTGER4PTGER2 | |
| SCHEMBL4450930 | 0.79 | PTGER4 (0.74) | PTGER4PTGER2KMT2A | |
| SCHEMBL4444927 | 0.79 | PTGER4 (0.74) | PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1867551-B | Phenyl or pyridyl amide compounds as prostaglandin E2 antagonists | RAQUALIA PHARMA INC | 2013-09-11 | — | — | CN | disclosed |
| CN-1946391-A | Combinations comprising alpha-2-delta ligands | PFIZER PROD INC (US) | 2007-04-11 | — | — | CN | disclosed |
| CN-1867551-A | Phenyl or pyridyl amide compounds as prostaglandin E2 antagonists | PFIZER (US) | 2006-11-22 | — | — | CN | disclosed |