Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27645418 | 0.84 | KDM4E (0.45) | TDP1KDM4EKMT2A | |
| SCHEMBL3554211 | 0.83 | KMT2A (0.42) | CNR1KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL4837442 | 0.81 | KDM4E (0.41) | CNR1KDM4EKMT2A | |
| Tert-Butyl Formate SCHEMBL27645414 | 0.72 | KDM4E (0.68) | TDP1KDM4EKMT2A | |
| Tert-Butyl Formate SCHEMBL28056935 | 0.72 | TDP1 (0.45) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27666527 | 0.72 | TDP1 (0.41) | TDP1KDM4EKMT2A | |
| SCHEMBL3561349 | 0.70 | KDM4E (0.55) | CNR1KDM4EKMT2A | |
| Tert-Butyl Formate SCHEMBL28078891 | 0.69 | TDP1 (0.45) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27947174 | 0.69 | TDP1 (0.54) | TDP1 | |
| SCHEMBL5395425 | 0.68 | KDM4E (0.43) | CNR1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1914182-B | Quinazoline derivatives | ASTRAZENECA AB | 2011-09-07 | — | — | CN | disclosed |
| CN-1914182-A | Quinazoline derivatives | ASTRAZENECA AB (SE) | 2007-02-14 | — | — | CN | disclosed |