Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL7756500 | 1.00 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL54771 | 1.00 | — | — | |
| Glycine SCHEMBL28019925 | 0.96 | — | — | |
| Glycine SCHEMBL5907901 | 0.96 | — | — | |
| Glycine SCHEMBL30898297 | 0.96 | — | — | |
| Glycine SCHEMBL8201410 | 0.96 | — | — | |
| Glycine SCHEMBL29262735 | 0.92 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL28348053 | 0.92 | — | — | |
| Glycine SCHEMBL4940394 | 0.92 | — | — | |
| Glycine SCHEMBL29749211 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100582227-C | Defibrase affinity separation material and defibrase affinity purification method | UNIV SHANGHAI JIAOTONG | 2010-01-20 | — | — | CN | disclosed |
| CN-1884507-A | Defibrase affinity separation material and defibrase affinity purification method | UNIV SHANGHAI JIAOTONG (CN) | 2006-12-27 | — | — | CN | disclosed |